NanoVector : Delivery of therapeutic molecules

With NanoVector, Affilogic is partnering with third parties to deliver their therapeutic compounds to specific cells / organs. We start our collaborations with existing Nanofitins® or through custom generation of Nanofitins® for our partners. Nanofitins® repeatedly demonstrated an efficient targeting in vivo towards specific cells. They can be selected for their capacity to internalize a payload via receptor-mediated cell uptake. A wide range of therapeutic molecules were efficiently combined with Nanofitins®, by genetic fusion (antibodies, enzymes, peptides…) or regio-selective chemical coupling (nanoparticles, nucleic acids, MMAE…) or expressed at the surface of cells. Plasmatic half-life of the conjugate can be increased with a Nanofitin® binding to albumin.

Delivery of multiple payloads using our Nanofitins, extracellularly or intracellularlyAlbumine binding Nanofitins for Half-life extension

Affilogic is always happy to work with partners to explore the targeted delivery of their innovative therapeutics. You want to target a specific cell type or tissue and have a target in mind ? Contact us, and we will explore together if Affilogic already has a Nanofitin® that suits your needs, or how we can discover and develop a Nanofitin® for you to answer your needs.